Suboxone Side Effects: What to Expect and How to Handle Them
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It’s critical to comprehend the advantages and potential drawbacks of Suboxone if you or someone you care about is taking it. For many people in recovery from opioid use disorder, suboxone is a medication that changes their lives. However, it may have mild or more serious side effects, just like any other treatment.
The good news? The majority of Suboxone side effects go away with time, and many can be controlled with the correct care. Our team of doctors at DevotedDOc is here to support you at every turn.
What Is Suboxone, and How Does It Work?

Suboxone is a combination of two medications:
- Buprenorphine helps reduce cravings and withdrawal symptoms.
- Naloxone discourages misuse and protects against improper use.
Together, they bind to opioid receptors in the brain, offering stability and relief without producing a โhigh.โ Suboxone is typically taken daily and gives people the chance to reclaim control of their recovery.
Why do side effects happen?
Suboxone works on both the brain and the body, so it takes time for your body to get used to it, especially if you were using opioids a lot before starting.
Your dosage, age, overall health, and any other medications you are taking can all change how your body reacts. Most people feel the effects of Suboxone within the first few days or weeks. A lot of them fade away over time. If they don’t, please talk to your doctor. We’re here to help
What does Suboxone do to you?

Everyone’s experience is different, but here are some of the most common side effects of Suboxone and how to deal with them:
- Headache: a dull or throbbing pain, especially at first. Drinking enough water and getting enough sleep can help.
- Nausea and vomiting: usually only for a short time. Eat small meals and try taking Suboxone after you eat.
- Sweating: is not dangerous, but it is uncomfortable. Drink plenty of water and wear layers.
- Constipation : is very common. Drink water, eat more fiber, and think about using a mild stool softener.
- Tiredness or sleepiness : Take a break when you need to, and don’t drive until you know how Suboxone affects you.
- Having trouble sleeping: usually gets better over time. If it doesn’t, talk to your provider.
Some patients also want to know, ” Can Suboxone cause fluid retention?” Swelling in the hands, ankles, or legs is not a common side effect, but it has happened in a few cases. Call your provider if you notice any strange swelling or weight gain.
“Does Suboxone make you lose weight?” is another common question. Some people say that their appetite or body weight changes while they are taking Suboxone, but it is not a weight-loss drug. This is different for everyone and has to do with their lifestyle, diet, and health in general.
Mental & Emotional Side Effects of Suboxone
Because Suboxone acts on the brain, some emotional or cognitive changes may occur:
- Anxiety โ Feeling jittery or restless? This may signal the need for a dosage adjustment.
- Mood changes or sadness โ Sometimes related to withdrawal or the recovery process. Support and counseling can help.
- Dizziness or lightheadedness โ Sit or lie down if needed, and rise slowly.
- Brain fog โ Trouble concentrating is common early on but usually fades.
- Suboxone personality changes โ Some people feel โdifferentโ emotionally in the early weeks. These changes often improve as your body stabilizes, but ongoing symptoms should be discussed with your doctor.
Oral and Mouth-Related Side Effects (Film Users)
If you use Suboxone film under the tongue or in the cheek, you may notice:
- Dry mouth โ Sip water or chew sugar-free gum.
- Burning or tingling โ A temporary irritation where the film touches.
- Mouth or tongue soreness โ If it persists, your provider may recommend a different form of medication.
Rare but Serious Side Effects
Most people tolerate Suboxone well, but itโs important to be aware of rare risks. Call 911 or seek immediate help if you notice:
- Breathing problems โ Shallow or slowed breathing, especially if combined with alcohol or sedatives.
- Suboxone allergic reaction โ Rash, swelling, itching, or difficulty breathing.
- Liver issues โ Yellowing skin or eyes, dark urine, or abdominal pain.
- suboxone personality changes โ Intense depression or thoughts of self-harm.
How to Deal with the Side Effects of Suboxone
Most side effects can be handled by making small changes to your daily life:
- Drink plenty of water and eat meals that are well-balanced.
- You should get enough sleep and do light exercise like walking.
- Keep track of your symptoms and tell your doctor about them.
- Use telehealth to get quick medical help without having to leave your home.
- It’s hard enough to get better. It shouldn’t be hard to deal with side effects.
Final Word From DevotedDOc
We have helped thousands of people start and stay on Suboxone safely at DevotedDOc.
We’re not here to judge you; we’re here to help you.
Most of the effects of Suboxone go away over time. Most of them are easy to deal with. And none of these things should stop you from getting better.
If you ever feel like you can’t handle it, don’t know what to do, or are confused, get in touch. You can easily connect with a trusted provider from the comfort of your own home with same-day telehealth visits.
Find Out More About Suboxone with DevotedDOc
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Frequently Asked Questions
The indictment alleges that Indivior falsely announced a discontinuance of its tablet form of Suboxone due to โconcerns regarding pediatric exposure,โ while knowing the real reason was to delay the FDA’s approval of generic alternatives. This move was part of a broader effort to maintain market control.
Suboxone can make a person feel very relaxed. While it’s effective in managing withdrawal symptoms, this relaxation can lead to a risk of developing a dependence. Common side effects include dizziness, nausea, and drowsiness.
Suboxone is beneficial in treating opioid addiction because it:
- Relieves severe withdrawal symptoms without causing a high
- Reduces cravings to support focus on recovery
- Blocks the effects of other opioids, helping prevent misuse
